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Prescription Lantus® (insulin glargine [rDNA origin] injection) is a long-acting insulin used to treat adults with type 2 diabetes and adults and pediatric patients (children 6 years and older) with type 1 diabetes for the control of high blood sugar. It should be taken once a day at the same time each day to lower blood glucose.

Do not use Lantus® to treat diabetic ketoacidosis.

Important Safety Information for Lantus® (insulin glargine [rDNA origin] injection)

Do not take Lantus® if you are allergic to insulin or any of the inactive ingredients in Lantus®.

Do not share needles, insulin pens or syringes with others. Do NOT reuse needles.

You must test your blood sugar levels while using insulin, such as Lantus®. Do not make any changes to your dose or type of insulin without talking to your healthcare provider. Any change of insulin should be made cautiously and only under medical supervision.

Do NOT dilute or mix Lantus® with any other insulin or solution. It will not work as intended and you may lose blood sugar control, which could be serious. Lantus® must only be used if the solution is clear and colorless with no particles visible.

Tell your doctor about other medicines, especially ones commonly called TZDs (thiazolidinediones), and supplements you are taking because they can change the way insulin works. Before starting Lantus®, tell your doctor about all your medical conditions including if you have heart failure or other heart problems, liver or kidney problems, are pregnant or planning to become pregnant, or are breast-feeding or planning to breast-feed. If you have heart failure, it may get worse while you take TZDs with Lantus®.

The most common side effect of insulin, including Lantus®, is low blood sugar (hypoglycemia), which may be serious. Some people may experience symptoms such as shaking, sweating, fast heartbeat, and blurred vision. Severe hypoglycemia may be serious and life threatening. It may cause harm to your heart or brain. Other possible side effects may include swelling, weight gain, injection site reactions, including changes in fat tissue at the injection site, and allergic reactions, including itching and rash. In rare cases, some allergic reactions may be life threatening.

Lantus® SoloSTAR® is a disposable prefilled insulin pen. Please talk to your healthcare provider about proper injection technique and follow instructions in the Instruction Leaflet that accompanies the pen.

Click here for Full Prescribing Information for Lantus®.

Click here for information on Sharps Medical Waste Disposal.

Click here to learn more about Sanofi's commitment to fighting counterfeit drugs.

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Insulin, Glucose and You

Insulin and Glucose

When you hear the word insulin, you may think of a drug taken by people who have diabetes.
While this is true, what you may not know is that insulin is one of the many hormones created in the human body.
Insulin is important to the body. It allows blood sugar (or glucose) to get into cells to provide them with energy.
When you eat, your body breaks down food into glucose in your small intestine.
This is your body's source of energy for everything it does, from working and thinking to exercising and healing.
Glucose travels through your bloodstream, looking for individual cells that need energy.
For glucose to get into the cells, it requires insulin.
Insulin is the key that unlocks cells for glucose to enter and deliver energy.
When insulin arrives, it signals the cell to activate glucose transporters.
These transporters pull glucose through cell walls.
When glucose moves into the cell, it delivers energy!

Insulin Deficiency

Insulin is normally produced in the pancreas.
When glucose enters your bloodstream, the pancreas matches it with the right amount of insulin to move glucose into your cells.
In people with type 2 diabetes, the pancreas may not be doing its entire job. It may produce less and less insulin over time.
If this happens, there isn't enough insulin in the bloodstream to unlock cells. With the cells locked, glucose can't get where it is needed to provide energy.

Insulin Resistance

In some type 2 diabetes patients, cells build up a resistance to insulin. Even though there may be enough insulin in the bloodstream, it can't unlock cells to allow glucose to enter.
As a result, it takes more insulin to find the right key to unlock the cell for glucose. This makes it more difficult for cells to get the energy they need.

The Effects of Diabetes

When glucose can't get into cells - either because there isn't enough insulin or because the body is resisting it, glucose begins to build up in the bloodstream.
As a result, all that energy is wasted. It does not get to cells where it is needed. Without glucose in your cells, they lack the energy they require to keep your body working.

Prescription Lantus® is a long-acting insulin used to treat adults with type 2 diabetes and adults and pediatric patients (children 6 years and older) with type 1 diabetes for the control of high blood sugar. It should be taken once a day at the same time each day to lower blood glucose.

Do not use Lantus® to treat diabetic ketoacidosis.

Important Safety Information for Lantus® (insulin glargine [rDNA origin] injection)

Do not take Lantus® if you are allergic to insulin or any of the inactive ingredients in Lantus®.

Please click here for additional Important Safety Information.

Please click here for Full Prescribing Information.

What is Toujeo®? (insulin glargine injection) 300 Units/mL

Prescription Toujeo® is a long-acting insulin used to control blood sugar in adults with diabetes mellitus.

  • Toujeo® contains 3 times as much insulin in 1 mL as standard insulin (100 Units/mL)
  • Toujeo® is not for use to treat diabetic ketoacidosis
  • Toujeo® should not be used in children
Important Safety Information for Toujeo® (insulin glargine injection) 300 Units/mL

Do not take Toujeo® during episodes of low blood sugar or if you are allergic to insulin or any of the inactive ingredients in Toujeo®.

Do not share insulin pens even if the needle has been changed. Do NOT reuse needles.

Before starting Toujeo®, tell your doctor about all your medical conditions, including:

  • If you have liver or kidney problems
  • If you are pregnant or planning to become pregnant
  • If you are breast-feeding or planning to breast-feed

Heart failure can occur if you are taking insulin together with certain medicines called TZDs (thiazolidinediones), even if you have never had heart failure or other heart problems. If you already have heart failure, it may get worse while you take TZDs with Toujeo®. Tell your doctor if you have any new or worsening symptoms of heart failure, including:

  • Shortness of breath
  • Swelling of your ankles or feet
  • Sudden weight gain

Your treatment with TZDs and TOUJEO® may need to be changed or stopped by your healthcare provider if you have new or worsening heart failure.

Tell your doctor about all the medications you take, including over-the-counter medicines, vitamins, and supplements, including herbal supplements.

Toujeo® should be taken once a day at the same time each day to lower blood glucose. You must test your blood sugar levels daily while using any insulin, including Toujeo®. Do not make any changes to your dose or type of insulin without talking to your healthcare provider. You should always verify that you have the correct insulin before each injection. Your dose for Toujeo® may be different from other insulins you have taken. Any change of insulin should be made cautiously and only under medical supervision.

Do NOT dilute or mix Toujeo® with any other insulin or solution. It will not work as intended and you may lose blood sugar control, which could be serious. Toujeo® must only be used if the solution is clear and colorless with no particles visible.

While using Toujeo®, do not drive or operate heavy machinery until you know how Toujeo® affects you. You should not drink alcohol or use other medicines that contain alcohol.

The most common side effect of any insulin, including Toujeo®, is low blood sugar (hypoglycemia), which may be serious and can be life-threatening. Severe hypoglycemia may cause harm to your heart or brain. Symptoms of serious low blood sugar may include shaking, sweating, fast heartbeat, and blurred vision. Toujeo® may cause serious side effects that can lead to death, such as severe allergic reactions that affect the whole body. Get medical help right away if you have:

  • A rash over your whole body
  • Trouble breathing
  • Shortness of breath
  • Fast heartbeat
  • Swelling of your face, tongue, or throat
  • Sweating
  • Extreme drowsiness, dizziness, or confusion

Toujeo® may have additional side effects. Other possible side effects may include swelling, weight gain, and low potassium.

Injection site reactions are also possible and may include change in fat tissue at the injection site, skin thickening, redness, swelling, and itching.

Toujeo® SoloStar® is a disposable prefilled insulin pen. Please talk to your healthcare provider about proper injection technique and follow instructions in the Instruction Leaflet that accompanies the pen.

Click here for Full Prescribing Information for Toujeo®.

US.GLA.15.02.040

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Important Safety Information for
Lantus® (insulin glargine [rDNA origin] injection)

Do not take Lantus® if you are allergic to insulin or any of the inactive ingredients in Lantus®.

Do not share needles, insulin pens or syringes with others. Do NOT reuse needles.

You must test your blood sugar levels while using insulin, such as Lantus®. Do not make any changes to your dose or type of insulin without talking to your healthcare provider. Any change of insulin should be made cautiously and only under medical supervision.

Do NOT dilute or mix Lantus® with any other insulin or solution. It will not work as intended and you may lose blood sugar control, which could be serious. Lantus® must only be used if the solution is clear and colorless with no particles visible.

Tell your doctor about other medicines, especially ones commonly called TZDs (thiazolidinediones), and supplements you are taking because they can change the way insulin works. Before starting Lantus®, tell your doctor about all your medical conditions including if you have heart failure or other heart problems, liver or kidney problems, are pregnant or planning to become pregnant, or are breast-feeding or planning to breast-feed. If you have heart failure, it may get worse while you take TZDs with Lantus®.

The most common side effect of insulin, including Lantus®, is low blood sugar (hypoglycemia), which may be serious. Some people may experience symptoms such as shaking, sweating, fast heartbeat, and blurred vision. Severe hypoglycemia may be serious and life threatening. It may cause harm to your heart or brain. Other possible side effects may include swelling, weight gain, injection site reactions, including changes in fat tissue at the injection site, and allergic reactions, including itching and rash. In rare cases, some allergic reactions may be life threatening.

Lantus® SoloSTAR® is a disposable prefilled insulin pen. Please talk to your healthcare provider about proper injection technique and follow instructions in the Instruction Leaflet that accompanies the pen.

Click here for Full Prescribing Information for Lantus®.
Click here for information on Sharps Medical Waste Disposal.
Click here to learn more about Sanofi's commitment to fighting counterfeit drugs.

The health information contained herein is provided for general educational purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment.